- Rachael Crawford
- Rachel
- Rachel Blanchard
- Rachel Hewitt
- Rachel Rhodes
- Rachel Runs For Office
- Radio CRAZ
- Rafhan Shaukat
- Ralph
- Ramona Barckert
- Ramona Milano
- Randal Edwards (Actor)
- Randall Edwards
- Randy
- Rasha Zuabi
- Ray of Light (1)
- Ray of Light (2)
- Raymond Ablack
- Re-Cycling Project
- Ready or Not
- Realm of Doom
- Rebecca Haines
- Rebecca Williams
- Red Pine Ascent Program for Troubled Teens
- Redemption Song
- Reese
- Regent
- Reiya Downs
- Relax
- Rescue You
- Retcon
- Reunited
- Reverend Baker
- Revolution!
- Rhonda Kristi
- Rhonda Patterson
- Ricardo Hoyos
- Richard Walters
- Richie Lawrence
- Rick-Caitlin Relationship
- Rick-Kathleen Conflict
- Rick Munro
- Rick Murray
- Riley-Anya Friendship
- Riley-Blue Friendship
- Riley-Drew Conflict
- Riley-Fiona Relationship
- Riley-Owen Conflict
- Riley-Sav Conflict
- Riley Gilchrist
- Riley Stavros
- RiseAndGrind
- Rivas v. Baker and Martin
- Robbie
- Robert Coyne
- Robert Kerwin
- Robert Mistysyn
- Robin Brûlé
- Robin Griffith
- Rock Dallas
- Rock This Town
- Rock and Roll High School
- Rodney's
- Rodrigo Palmeiro
- Roger Montgomery
- RollUpToTheClubLike
- Romeo and Jules
- Ron-Ron
- Roomatus Interuptus
- Roommate Code of Conduct
- Rose Michalchuk
- Rose Newlove
- Ross Churchill
- Rudy Novak
- Rufus Eggers
- Rumor Has It
- Rumours and Reputations
- Rusty Cage (1)
- Rusty Cage (2)
- Ruth Marshall
- Ryan Cooley
- Ryan Runs for Help
- Saad-Abra (Siblings)
- Saad-Lola Relationship
- Saad-Maya Friendship
- Saad Al'Maliki
- Saara Chaudry
- Sabotage (1)
- Sabotage (2)
- Sadie Rowland
- Salesman
- Sally
- Sam
- Sam Earle
- Samantha
- Samantha Brown
- Samantha Gets A Visitor
- Samantha Munro
- Samii Folliott
- Samira
- Sara Ballingall
- Sara Holmes
- Sara Waisglass
- Sarah Barrable-Tishauer
- Sarah Charlesworth
- Sarah Fisher
- Sarena Parmar
- Sav-Alli (Siblings)
- Sav-Anya-Farrah Love Triangle
- Sav-Anya-Riley Love Triangle
- Sav-Anya Relationship
- Sav-Chantay Friendship
- Sav-Drew Friendship
- Sav-Holly J.-Declan Love Triangle
- Sav-Holly J.-Jenna Love Triangle
- Sav-Holly J.-Mia Love Triangle
- Sav-Holly J. Relationship
- Sav-Jane Friendship
- Sav-Jenna Friendship
- Sav-Keke Friendship
- Sav-Mo Friendship
- Sav-Winnie Relationship
- Sav Bhandari
- Say It Ain't So (1)
- Say It Ain't So (2)
- School's Out!
- Schuyler High School
- Schuyler Stadium
- Science Olympics
- Scooter Webster
- Scott Beaudin
- Scott Paterson
- Scott Smith
- Scream (1)
- Scream (2)
- Sealed With a Kiss
- Sean-Alex Friendship
- Sean-Amy Relationship
- Sean-Ashley Friendship
- Sean-Craig Friendship
- Sean-Ellie Relationship
- Sean-Emma-Jay Love Triangle
- Sean-Emma-Toby Love Triangle
- Sean-Emma Relationship
- Sean-J.T. Friendship
- Sean-Jay Friendship
- Sean-Jimmy Conflict
- Sean-Manny Friendship
- Sean-Marco Friendship
- Sean-Peter Conflict
- Sean-Spinner Friendship
- Sean-Tracker (Siblings)
- Sean-Tyler Conflict
- Sean Bell
- Sean Cameron
- Sean in Prison
- Searching for Sinder3lla
- Season's Greetings
- Season 1
- Season 10 Degrassi Music
- Season 2
- Season 3
- Season 4
- Seaway Pharmacy
- Secret (1)
- Secret (2)
- Secrets and Lies
- Shane
- Shane-Christine Relationship
- Shane (book)
- Shane Dawson's Degrassi Parody
- Shane Kippel
- Shane McKay
- Shanice Banton
- Shannon Kook-Chun
- Shark in the Water
- Shauna MacDonald
- Shawn Biso
- Shawn Roberts
- Shay-Arlene Conflict
- Shay-Esme Conflict
- Shay-Frankie Friendship
- Shay-Goldi Friendship
- Shay-Lola Friendship
- Shay-Zoë Friendship
- Shay Mitchell
- Shay Powers
- Sheila
- Sheila Brogren
- Shelley Scarrow
- Shenae Grimes
- Sherm
- Shine
- Shirley Douglas
- Shoot to Thrill
- Shoppers Drug Mart
- Should've Said No (1)
- Should've Said No (2)
- Should I Stay or Should I Go?
- Shout (1)
- Shout (2)
- Showtime (1)
- Showtime (2)
- Siluck Saysanasy
- Simcoe Elementary School
- Similarities Throughout The Franchise
- Simon-Alexa Relationship
- Simon Dexter
- SinceWeBeinHonest
- Siobhan
- Sir Excellence
- Sirina
- Six Months
- Sixteen
- Skinny
- Sky Light Photo Services
- Smash Into You (1)
- Smash Into You (2)
- Smells Like Teen Spirit
- Smithdale University
- Smokescreen
- Snake (book)
- Soma Bhatia
- Somebody
- Someone
- Something's Got to Give
- Songs from Degrassi: The Next Generation
- Sonia Dhillon Tully
- Sophia Rosen
- Sophie Brendakis
- Sophie Minds the Store
- Sopjia OhLeary
- SorryNotSorry
- Space Awakening
- Sparks Will Fly (1)
- Sparks Will Fly (2)
- Spencer MacPherson
- Spencer Van Wyck
- Spiderwebs
- Spike-Manny Friendship
- Spike (book)
- Spinner's Loft
- Spinner's Turtle
- Spinner-Ashley Friendship
- Spinner-Craig Friendship
- Spinner-Darcy-Paige Love Triangle
- Spinner-Darcy Relationship
- Spinner-Declan Conflict
- Spinner-Emma-Jane Love Triangle
- Spinner-Emma Relationship
- Spinner-Holly J. Friendship
- Spinner-J.T. Conflict
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